ASTM D5196-91(1999) - 10.10.1999
 
1. Scope

1.1 This guide is intended to describe the physical and chemical characteristics of water to be used whenever critical purity is essential to the use intended in clinical, pharmaceutical, biophysical, biomedical, chemical, physical research applications, or a combination of these. This guide is not intended for use in preparing water for injectables. Generally, the appropriate use of this guide may include experiments involving tissue culture, chromatography, mass spectroscopy, or analysis where molecular quantities of impurities may be important.

1.2 This standard does not purport to address all of the safety problems, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use.

 
2. Referenced Documents

D4453-17(2025)

Standard Practice for Handling of High Purity Water Samples

D5127-13(2018)

Standard Guide for Ultra-Pure Water Used in the Electronics and Semiconductor Industries

D1193-24

Standard Specification for Reagent Water

D1125-23

Standard Test Methods for Electrical Conductivity and Resistivity of Water

D1129-24

Standard Terminology Relating to Water

D5173-15(2023)

Standard Guide for On-Line Monitoring of Total Organic Carbon in Water by Oxidation and Detection of Resulting Carbon Dioxide

D5245-19(2024)

Standard Practice for Cleaning Laboratory Glassware, Plasticware, and Equipment Used in Microbiological Analyses

D5391-23

Standard Test Method for Electrical Conductivity and Resistivity of a Flowing High Purity Water Sample

D5542-16

Standard Test Methods for Trace Anions in High Purity Water by Ion Chromatography (Withdrawn 2025)

D5673-16(2024)e1

Standard Test Method for Elements in Water by Inductively Coupled Plasma—Mass Spectrometry (Includes all amendments and changes 1/13/2025).

D5996-16

Standard Test Method for Measuring Anionic Contaminants in High-Purity Water by On-Line Ion Chromatography (Withdrawn 2025)

F1094-87(1999)

Standard Test Methods for Microbiological Monitoring of Water Used for Processing Electron and Microelectronic Devices by Direct Pressure Tap Sampling Valve and by the Presterilized Plastic Bag Method