This practice summarizes the steps in the antimicrobial pesticide selection process, reviewing technical and regulatory considerations inherent in the process. It complements and amplifies information provided in Practice E 1497.

5.1.1 Steps in the antimicrobial selection process include: needs identification, use strategy selection, efficacy testing, chemical compatibility testing, regulatory consideration review, handling and disposal issue review.

This practice provides stakeholders in the microbicide selection process an overview of its complexities, including the process of obtaining pesticide registration from cognizant governing bodies.

Personnel responsible for antimicrobial pesticide selection will be able to use this practice as a roadmap through the process.

Personnel responsible for industrial hygiene, product or plant management will gain insight to the tradeoffs attendant with antimicrobial use and selection.

1.1 This practice provides recommendations for selecting antimicrobial pesticides (microbicides) for use in water-miscible metalworking fluids (MWF). It presents information regarding regulatory requirements, as well as technical factors including target microbes, efficacy and chemical compatibility.

1.2 This guide is not an encyclopedic compilation of all the concepts and terminology uses by chemists, microbiologists, toxicologists, formulators, plant engineers and regulatory affairs specialists involved in antimicrobial pesticide selection and application. Instead, it provides a general understanding of the selection process and its supporting considerations.

1.3 The values in SI units are to be regarded as the standard.

This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use.