ASTM E2402-11(2017) - 15.12.2017
 
Significance and Use

5.1 This test method may be used to validate the performance of a specific TGA apparatus.

5.2 This test method may be used to validate the performance of a specific method based upon a TGA mass loss or residue measurement.

5.3 This test method may be used to determine the repeatability of a specific apparatus, operator or laboratory.

5.4 This test method may be used for specification and regulatory compliance purposes.

 
1. Scope

1.1 This test method provides procedures for validating mass loss and residue measurements by thermogravimetric analyzers (TGA) and analytical methods based upon the measurement of mass loss or residue content. Performance parameters determined include mass loss and residue repeatability (precision), detection limit, quantitation limit, linearity, and bias.

1.2 Validation of apparatus performance and analytical methods is requested or required for quality initiatives or where results may be used for legal purposes.

1.3 The values stated in SI units are to be regarded as standard. No other units of measurement are included in this standard.

1.4 There is no ISO standard equivalent to this test method.

1.5 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety, health, and environmental practices and determine the applicability of regulatory limitations prior to use.

1.6 This international standard was developed in accordance with internationally recognized principles on standardization established in the Decision on Principles for the Development of International Standards, Guides and Recommendations issued by the World Trade Organization Technical Barriers to Trade (TBT) Committee.

 
2. Referenced Documents

E2161-23c

Standard Terminology Relating to Performance Validation in Thermal Analysis and Rheology (Includes all amendments and changes 8/17/2023).

United States Food and Drug Administration,

Q2B Validation of Analytical Procedures: Methodology, 62 FR 27464, May 19, 1997 Available from Food and Drug Administration (FDA), 10903 New Hampshire Ave., Silver Spring, MD 20993-0002, http://www.fda.gov.

E177-20

Standard Practice for Use of the Terms Precision and Bias in ASTM Test Methods

E1970-23

Standard Practice for Statistical Treatment of Thermoanalytical Data

E1582-21

Standard Test Method for Temperature Calibration of Thermogravimetric Analyzers

E1142-23b

Standard Terminology Relating to Thermophysical Properties (Includes all amendments and changes 10/5/2023).

E473-23b

Standard Terminology Relating to Thermal Analysis and Rheology (Includes all amendments and changes 10/5/2023).

E2040-19

Standard Test Method for Mass Scale Calibration of Thermogravimetric Analyzers