ASTM E2548-16 - 1.3.2016
 
Significance and Use

3.1 This guide provides information for the sampling of seized-drug submissions.

3.2 The principal purpose of sampling in the context of this guide is to answer relevant questions about a population by examination of a portion of the population. For example:

 

What is the net weight of the population?

 

What portion of the units of a population can be said to contain a given drug at a given level of confidence?

3.3 By developing a sampling strategy and implementing appropriate sampling schemes, as illustrated in Fig. 1, a laboratory will minimize the total number of required analytical determinations, while ensuring that all relevant legal and scientific requirements are met.

 
1. Scope

1.1 This guide covers minimum considerations for sampling of seized drugs for qualitative and quantitative analysis.

1.2 This guide cannot replace knowledge, skill, or ability acquired through appropriate education, training, and experience and should be used in conjunction with sound professional judgment.

 
2. Referenced Documents

E2334-09(2023)

Standard Practice for Setting an Upper Confidence Bound for a Fraction or Number of Non-Conforming items, or a Rate of Occurrence for Non-Conformities, Using Attribute Data, When There is a Zero Response in the Sample

E105-21

Standard Guide for Probability Sampling of Materials

E2329-17

Standard Practice for Identification of Seized Drugs

E1732-24

Standard Terminology Relating to Forensic Science

E141-10(2023)

Standard Practice for Acceptance of Evidence Based on the Results of Probability Sampling

E122-17(2022)

Standard Practice for Calculating Sample Size to Estimate, With Specified Precision, the Average for a Characteristic of a Lot or Process

ISO 3534-2

Statistics Vocabulary and Symbols Part 2: Statistical Quality Control

ISO 3534-1